Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.-论文-万方医学网

作者： Wei,Xia ^[1] ; Jing,Xie ^[1] ; Zhiqing,Cai ^[1] ; Xuhua,Liu ^[2] ; Jing,Wen ^[3] ; Zhong-Kai,Cui ^[1] ; Run,Zhao ^[1] ; Xiaomei,Zhou ^[1] ; Jiahui,Chen ^[2] ; Xinru,Mao ^[4] ; Zhengtao,Gu ^[5] ; Zhimin,Zou ^[5] ; Zhipeng,Zou ^[1] ; Yue,Zhang ^[1] ; Ming,Zhao ^[5] ; Maegele,Mac ^[6] ; Qiancheng,Song ^[7] ; Xiaochun,Bai ^[8]

作者单位： Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. ^[1] State Key Laboratory of Organ Failure Research, Academy of Orthopedics, Guangdong Province, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, 510630, China. ^[2] Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ^[3] Department of Clinical laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ^[4] Department of Pathophysiology, Guangdong Provincial Key Laboratory of Shock and Microcirculation Research, Southern Medical University, Guangzhou, Guangdong, 510515, China. ^[5] Institute for Research in Operative Medicine, Private University of Witten-Herdecke, Cologne Merheim Medical Center, Ostmerheimerstr 200, D-51109, Cologne, Germany. ^[6] Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. songqc@smu.edu.cn. ^[7] Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China. baixc15@smu.edu.cn. ^[8]

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);动物(Animals);骨和骨组织(Bone and Bones);脑(Brain);脑损伤(Brain Injuries);细胞系(Cell Line);疾病模型, 动物(Disease Models, Animal);叉头转录因子类(Forkhead Transcription Factors);人类(Humans);男(雄)性(Male);微RNAs(MicroRNAs);中年人(Middle Aged);神经元(Neurons);神经生理学(Neurophysiology);骨生成(Osteogenesis);蛋白质组学(Proteomics);大鼠(Rats);风湿性疾病(Rheumatic Diseases);伤口愈合(Wound Healing);青年人(Young Adult)

DOI 10.1038/s41467-021-26302-y

PMID 34654817

发布时间 2021-11-12

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Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.

Nature communications

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Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.

Nature communications

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Nature communications

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