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The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.

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作者单位: Division of Cancer Cell Biology, Cancer Research Institute, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan. [1] Division of Molecular Therapy, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan. [2] Division of Hematological Malignancy, National Cancer Center Research Institute, Tokyo 104-0045, Japan. [3] Division of Functional Genomics, Cancer Research Institute, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan. [4] Laboratory of Developmental Genetics, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan. [5] Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan. [6] Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan. [7] Department of Diagnostic Radiology, Kitasato University of School of Medicine, Sagamihara City 252-0373, Japan. [8] Department of Anatomy, National Defense Medical College, Tokorozawa 359-8513, Japan. [9] Department of Medicine and Biosystemic Science, Graduate School of Medicine, Kyushu University, Fukuoka 812-8582, Japan. [10] Division of Gene Regulation, Institute of Advanced Medical Research, Keio University, Tokyo 160-8582, Japan. [11] Department of Molecular Pathology, Tokyo Medical University, Tokyo 160-8402, Japan. [12] Cancer Research Institute, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan. [13] Division of Cancer Cell Biology, Cancer Research Institute, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan; ngotoh@staff.kanazawa-u.ac.jp. [14]
DOI 10.1073/pnas.2103658118
PMID 34663724
发布时间 2021-12-14
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Proceedings of the National Academy of Sciences of the United States of America

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