A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle.

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作者： Kelsey L,Lynch ^[1] ; Melanie R,Dillon ^[1] ; Mongoljin,Bat-Erdene ^[1] ; Hannah C,Lewis ^[2] ; Robin J,Kaai ^[2] ; Edward A,Arnold ^[3] ; Daphne C,Avgousti ^[4]

作者单位： Human Biology Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA. ^[1] Human Biology Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA; Molecular & Cellular Biology in Seattle, Graduate Program, University of Washington and Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA. ^[2] Human Biology Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA; Microbiology Graduate Program, University of Washington, 1705 NE Pacific Street, Box 357735, Seattle, WA 98195, USA. ^[3] Human Biology Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA; Molecular & Cellular Biology in Seattle, Graduate Program, University of Washington and Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA; Microbiology Graduate Program, University of Washington, 1705 NE Pacific Street, Box 357735, Seattle, WA 98195, USA. Electronic address: avgousti@fredhutch.org. ^[4]

关键词 HMGB proteins adenovirus budding yeast cell cycle chromatin linker histone molecular virology

主题词细胞周期(Cell Cycle);染色质(Chromatin);HMGB蛋白质类(HMGB Proteins);组蛋白类(Histones);人类(Humans);酿酒酵母菌(Saccharomyces cerevisiae);病毒蛋白质类(Viral Proteins)

DOI 10.1016/j.cub.2021.09.050

PMID 34666003

发布时间 2022-12-07

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