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An original methodology to study polymeric nanoparticle-macrophage interactions: Nanoparticle tracking analysis in cell culture media and quantification of the internalized objects.

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第一作者： Tom,Bourguignon

第一单位： Université Paris-Saclay, CNRS, Institut des Sciences Moléculaires d'Orsay, 91405 Orsay, France.

作者： Tom,Bourguignon ^[1] ; Adriano A,Torrano ^[2] ; Ludivine,Houel-Renault ^[1] ; Arnaud,Machelart ^[3] ; Priscille,Brodin ^[3] ; Ruxandra,Gref ^[4]

作者单位： Université Paris-Saclay, CNRS, Institut des Sciences Moléculaires d'Orsay, 91405 Orsay, France. ^[1] University of Munich (LMU), Department of Chemistry and Center for NanoScience (CeNS), 81377 Munich, Germany. ^[2] Université de Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France. ^[3] Université Paris-Saclay, CNRS, Institut des Sciences Moléculaires d'Orsay, 91405 Orsay, France. Electronic address: ruxandra.gref@universite-paris-saclay.fr. ^[4]

关键词 Cellular uptake Confocal microscopy Dynamic light scattering Nanoparticle tracking analysis Poly(lactic acid)Polymer nanoparticle Size distribution

医学主题词细胞培养技术(Cell Culture Techniques);药物载体(Drug Carriers);乳酸(Lactic Acid);巨噬细胞(Macrophages);纳米粒子(Nanoparticles);粒子大小(Particle Size);聚乙醇酸(Polyglycolic Acid)

DOI 10.1016/j.ijpharm.2021.121202

PMID 34666144

发布时间 2021-12-14

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