Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex.

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第一作者： Dmitriy Y,Ryazantsev

第一单位： Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.

作者： Dmitriy Y,Ryazantsev ^[1] ; Mikhail Yu,Myshkin ^[1] ; Vera A,Alferova ^[1] ; Vladimir B,Tsvetkov ^[2] ; Elena Y,Shustova ^[3] ; Polina N,Kamzeeva ^[4] ; Polina V,Kovalets ^[5] ; Elvira R,Zaitseva ^[1] ; Nadezhda S,Baleeva ^[6] ; Timofei S,Zatsepin ^[1] ; Zakhar O,Shenkarev ^[1] ; Mikhail S,Baranov ^[6] ; Liubov I,Kozlovskaya ^[1] ; Andrey V,Aralov ^[7]

作者单位： Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. ^[1] Gause Institute of New Antibiotics, B. Pirogovskaya 11, 119021 Moscow, Russia. ^[2] World-Class Research Center "Digital Biodesign and Personalized Healthcare", Sechenov First Moscow State Medical University, 8/2 Trubetskaya Str., 119146 Moscow, Russia. ^[3] Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia. ^[4] Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences, 108819 Moscow, Russia. ^[5] D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Sq., 125047 Moscow, Russia. ^[6] Pirogov Russian National Research Medical University, Ostrovitianov 1, 117997 Moscow, Russia. ^[7] Center for Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia. ^[8] Sechenov First Moscow State Medical University, 119991 Moscow, Russia. ^[9] G4_Interact, USERN, University of Pavia, 27100 Pavia, Italy. ^[10]

关键词 FRET-melting G-quadruplex antiviral activity cytotoxicity green fluorescent protein (GFP) chromophore

主题词抗HIV药(Anti-HIV Agents);G四链体(G-Quadruplexes);绿色荧光蛋白质类(Green Fluorescent Proteins);HIV感染(HIV Infections);HIV长末端重复序列(HIV Long Terminal Repeat);HIV-1(HIV-1);人类(Humans);磁共振波谱学(Magnetic Resonance Spectroscopy);模型, 分子(Models, Molecular);构效关系(Structure-Activity Relationship)

DOI 10.3390/biom11101409

PMID 34680042

发布时间 2022-01-19

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Biomolecules

2021年11卷10期

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Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex.

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Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex.

Biomolecules

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Biomolecules

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