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Comparing the Fasting and Random-Fed Metabolome Response to an Oral Glucose Tolerance Test in Children and Adolescents: Implications of Sex, Obesity, and Insulin Resistance.

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第一作者： Jennifer L,LaBarre

第一单位： Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.;Department of Medicine, Dartmouth-Hitchcock Medical Center, Weight and Wellness Center, Lebanon, NH 03766, USA.

作者： Jennifer L,LaBarre ^[1] ; Emily,Hirschfeld ^[2] ; Tanu,Soni ^[3] ; Maureen,Kachman ^[3] ; Janis,Wigginton ^[3] ; William,Duren ^[4] ; Johanna Y,Fleischman ^[5] ; Alla,Karnovsky ^[6] ; Charles F,Burant ^[7] ; Joyce M,Lee ^[8]

作者单位： Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.;Department of Medicine, Dartmouth-Hitchcock Medical Center, Weight and Wellness Center, Lebanon, NH 03766, USA. ^[1] Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA. ^[2] Michigan Regional Comprehensive Metabolomics Resource Core, University of Michigan, Ann Arbor, MI 48109, USA. ^[3] Michigan Regional Comprehensive Metabolomics Resource Core, University of Michigan, Ann Arbor, MI 48109, USA.;Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA. ^[4] Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. ^[5] Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109, USA. ^[6] Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.;Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. ^[7] Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA.;Division of Pediatric Endocrinology, Department of Pediatrics, University of Michigan, Ann Arbor, MI 48109, USA. ^[8]

关键词 acylcarnitines adolescents fatty acids glucose challenge insulin resistance metabolomics obesity oral glucose tolerance test