Chemical Genetic Screen in <i>Drosophila</i> Germline Uncovers Small Molecule Drugs That Sensitize Stem Cells to Insult-Induced Apoptosis.

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作者： Julien Roy,Ishibashi ^[1] ; Riya,Keshri ^[2] ; Tommy Henry,Taslim ^[1] ; Daniel Kennedy,Brewer ^[2] ; Tung Ching,Chan ^[1] ; Scott,Lyons ^[2] ; Anika Marie,McManamen ^[1] ; Ashley,Chen ^[2] ; Debra,Del Castillo ^[1] ; Hannele,Ruohola-Baker ^[2]

作者单位： Department of Biochemistry, University of Washington, Seattle, WA 98195, USA. ^[1] Institute for Stem Cell and Regenerative Medicine, School of Medicine, University of Washington, Seattle, WA 98109, USA. ^[2]

关键词 Drosophila apoptosis cancer germline quiescence radiation small molecule stem cells

主题词动物(Animals);细胞凋亡(Apoptosis);乳腺肿瘤(Breast Neoplasms);黑腹果蝇(Drosophila melanogaster);女(雌)性(Female);基因检测(Genetic Testing);生殖细胞(Germ Cells);人类(Humans);男(雄)性(Male);类器官(Organoids);卵巢(Ovary);药用制剂(Pharmaceutical Preparations);RNA干扰(RNA Interference);小分子化合物库(Small Molecule Libraries);干细胞(Stem Cells);睾丸(Testis)

DOI 10.3390/cells10102771

PMID 34685753

发布时间 2021-11-30

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2021年10卷10期

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Chemical Genetic Screen in <i>Drosophila</i> Germline Uncovers Small Molecule Drugs That Sensitize Stem Cells to Insult-Induced Apoptosis.

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Chemical Genetic Screen in <i>Drosophila</i> Germline Uncovers Small Molecule Drugs That Sensitize Stem Cells to Insult-Induced Apoptosis.

Cells

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