Hsa_circ_0004296 inhibits metastasis of prostate cancer by interacting with EIF4A3 to prevent nuclear export of ETS1 mRNA.
第一作者:
Shiyu,Mao
第一单位:
Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yan Chang Road, Shanghai, 200072, P. R. China.
作者:
医学主题词
主动转运, 细胞核(Active Transport, Cell Nucleus);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);计算生物学(Computational Biology);DEAD-box RNA解旋酶类(DEAD-box RNA Helicases);疾病模型, 动物(Disease Models, Animal);真核细胞起始因子4A(Eukaryotic Initiation Factor-4A);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);人类(Humans);男(雄)性(Male);小鼠(Mice);模型, 生物学(Models, Biological);前列腺肿瘤(Prostatic Neoplasms);蛋白质结合(Protein Binding);原癌基因蛋白质c-ets-1(Proto-Oncogene Protein c-ets-1);RNA, 信使(RNA, Messenger)
DOI
10.1186/s13046-021-02138-8
PMID
34696782
发布时间
2022-02-01
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