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Untargeted Metabolome- and Transcriptome-Wide Association Study Suggests Causal Genes Modulating Metabolite Concentrations in Urine.

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第一作者： Reyhan,Sönmez Flitman

第一单位： Department of Computational Biology, University of Lausanne, Lausanne 1015, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.

作者： Reyhan,Sönmez Flitman ^[1] ; Bita,Khalili ^[1] ; Zoltan,Kutalik ^[2] ; Rico,Rueedi ^[1] ; Anneke,Brümmer ^[1] ; Sven,Bergmann ^[3]

作者单位： Department of Computational Biology, University of Lausanne, Lausanne 1015, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland. ^[1] Department of Computational Biology, University of Lausanne, Lausanne 1015, Switzerland.;University Center for Primary Care and Public Health, University of Lausanne, Lausanne 1010, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland. ^[2] Department of Computational Biology, University of Lausanne, Lausanne 1015, Switzerland.;Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.;Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town 7700, South Africa. ^[3]

关键词 ALMS1 HPS1 N-acetylated compounds NAT8 PYROXD2 genome-wide association study metabolomics transcriptomics trimethylamine

主题词体液(Body Fluids);人类(Humans);磁共振波谱学(Magnetic Resonance Spectroscopy);代谢组(Metabolome);代谢组学(Metabolomics)

DOI 10.1021/acs.jproteome.1c00585

PMID 34699229

发布时间 2022-07-18

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