Novel temporal and spatial patterns of metastatic colonization from breast cancer rapid-autopsy tumor biopsies.

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作者： Xiaomeng,Huang ^[1] ; Yi,Qiao ^[2] ; Samuel W,Brady ^[1] ; Rachel E,Factor ^[2] ; Erinn,Downs-Kelly ^[3] ; Andrew,Farrell ^[4] ; Jasmine A,McQuerry ^[5] ; Gajendra,Shrestha ^[5] ; David,Jenkins ^[1] ; W Evan,Johnson ^[2] ; Adam L,Cohen ^[3] ; Andrea H,Bild ^[6] ; Gabor T,Marth ^[3]

作者单位： Utah Center for Genetic Discovery, University of Utah, Salt Lake City, USA. ^[1] Department of Human Genetics, School of Medicine, University of Utah, Salt Lake City, USA. ^[2] Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, USA. ^[3] Department of Biomedical Informatics, School of Medicine, University of Utah, Salt Lake City, USA. ^[4] Department of Pathology, School of Medicine, University of Utah, Salt Lake City, USA. ^[5] Department of Oncological Sciences, School of Medicine, University of Utah, Salt Lake City, USA. ^[6] Computational Biomedicine, Department of Medicine, Boston University, Boston, USA. ^[7] Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, USA. ^[8] Department of Medical Oncology & Therapeutics Research, City of Hope, Duarte, USA. ^[9] Utah Center for Genetic Discovery, University of Utah, Salt Lake City, USA. gabor.marth@gmail.com. ^[10] Department of Human Genetics, School of Medicine, University of Utah, Salt Lake City, USA. gabor.marth@gmail.com. ^[11]

关键词 Metastatic breast cancer Subclone Tumor evolution