首页> Cytotherapy> Response to extracorporeal photopheresis therapy of patients with steroid-refractory/-resistant GvHD is associated with up-regulation of Th22 cells and Tfh cells.

Response to extracorporeal photopheresis therapy of patients with steroid-refractory/-resistant GvHD is associated with up-regulation of Th22 cells and Tfh cells.

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第一作者： Ming,Ni

第一单位： Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany; Department of Hematology, the Affiliated Hospital of Guizhou Medical University, Guizhou, China.

作者： Ming,Ni ^[1] ; Lei,Wang ^[2] ; Yuntian,Ding ^[2] ; Wenjie,Gong ^[3] ; Sanmei,Wang ^[4] ; Brigitte,Neuber ^[2] ; Maria-Luisa,Schubert ^[2] ; Tim,Sauer ^[2] ; Angela,Hückelhoven-Krauss ^[2] ; Thomas,Luft ^[2] ; Ute,Hegenbart ^[2] ; Stefan,Schönland ^[2] ; Volker,Eckstein ^[2] ; Jishi,Wang ^[5] ; William,Krüger ^[6] ; Carsten,Müller-Tidow ^[2] ; Peter,Dreger ^[2] ; Michael,Schmitt ^[2] ; Anita,Schmitt ^[7]

作者单位： Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany; Department of Hematology, the Affiliated Hospital of Guizhou Medical University, Guizhou, China. ^[1] Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany. ^[2] Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany; Department of Hematology, the First Affiliated Hospital of Soochow University, Suzhou, China. ^[3] Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany; Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China. ^[4] Department of Hematology, the Affiliated Hospital of Guizhou Medical University, Guizhou, China. ^[5] Department of Internal Medicine C, Haematology, Oncology, Stem Cell Transplantation, Palliative Care, University Clinic Greifswald, Greifswald, Germany. ^[6] Department of Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany. Electronic address: anita.schmitt@med.uni-heidelberg.de. ^[7]

关键词 ECP Fas-mediated apoptosis GvHD Th cells immune checkpoint molecules immunomodulation

医学主题词 CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);慢性病(Chronic Disease);移植物抗宿主病(Graft vs Host Disease);人类(Humans);体外光化学疗法(Photopheresis);甾类(Steroids);增量调节(Up-Regulation)

DOI 10.1016/j.jcyt.2021.09.008

PMID 34711501

发布时间 2022-04-25

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