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Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system.

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第一作者： Lisa Sophie,Pflüger

第一单位： Center for Diagnostics, Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.;I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

作者： Lisa Sophie,Pflüger ^[1] ; Dominik,Nörz ^[2] ; Tassilo,Volz ^[3] ; Katja,Giersch ^[3] ; Annika,Giese ^[4] ; Nora,Goldmann ^[4] ; Dieter,Glebe ^[4] ; Jan-Hendrik,Bockmann ^[5] ; Susanne,Pfefferle ^[2] ; Maura,Dandri ^[5] ; Julian,Schulze Zur Wiesch ^[5] ; Marc,Lütgehetmann ^[6]

作者单位： Center for Diagnostics, Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.;I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. ^[1] Center for Diagnostics, Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. ^[2] I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany. ^[3] Institute of Medical Virology, National Reference Centre for Hepatitis B Viruses and Hepatitis D Viruses, Justus Liebig University Giessen, Giessen, Germany.;German Center for Infection Research (DZIF), Giessen-Marburg-Langen, Germany. ^[4] I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.;German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany. ^[5] Center for Diagnostics, Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.;German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany. ^[6]

关键词 CE-IVD, CE-marked in?vitro diagnostics EQA, external quality assessment GT, genotypes HDV, Hepatitis delta virus HDV_UCT, HDV utility-channel LLOD, lower limit of detection RT-qPCR, Real time reverse transcription polymerase chain reaction RT-qPCR, reverse transcription quantitative real-time PCR WHO, world health organization cHDV, chronic HDV infection cobas6800 molecular diagnostics quantification viral hepatitis

DOI 10.1016/j.jhepr.2021.100356

PMID 34712932

发布时间 2022-04-27

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Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system.

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