A Randomized, Placebo-Controlled Clinical Trial of Bamlanivimab and Etesevimab Together in High-Risk Ambulatory Patients With COVID-19 and Validation of the Prognostic Value of Persistently High Viral Load.

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第一作者： Michael,Dougan

第一单位： Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

作者： Michael,Dougan ^[1] ; Masoud,Azizad ^[2] ; Bharat,Mocherla ^[3] ; Robert L,Gottlieb ^[4] ; Peter,Chen ^[5] ; Corey,Hebert ^[6] ; Russell,Perry ^[7] ; Joseph,Boscia ^[8] ; Barry,Heller ^[9] ; Jason,Morris ^[10] ; Chad,Crystal ^[11] ; Awawu,Igbinadolor ^[12] ; Gregory,Huhn ^[13] ; Jose,Cardona ^[14] ; Imad,Shawa ^[15] ; Princy,Kumar ^[16] ; Andra,Blomkalns ^[17] ; Andrew C,Adams ^[18] ; Jacob,Van Naarden ^[19] ; Kenneth L,Custer ^[19] ; Jack,Knorr ^[19] ; Gerard,Oakley ^[19] ; Andrew E,Schade ^[19] ; Timothy R,Holzer ^[19] ; Philip J,Ebert ^[19] ; Richard E,Higgs ^[19] ; Janelle,Sabo ^[19] ; Dipak R,Patel ^[19] ; Matan C,Dabora ^[19] ; Mark,Williams ^[19] ; Paul,Klekotka ^[19] ; Lei,Shen ^[19] ; Daniel M,Skovronsky ^[19] ; Ajay,Nirula ^[19]

作者单位： Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. ^[1] Valley Clinical Trials Northridge, Northridge, California, USA. ^[2] Las Vegas Medical Research Center, Las Vegas, Nevada, USA. ^[3] Baylor University Medical Center, Dallas, Texas, USA. ^[4] Baylor Scott and White Research Institute, Dallas, Texas, USA. ^[5] Department of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. ^[6] NOLA Research Works, New Orleans, Louisiana, USA. ^[7] Gadolin Research, Beaumont, Texas, USA. ^[8] Vitalink Research, Union, South Carolina, USA. ^[9] Long Beach Clinical Trials, Long Beach, California, USA. ^[10] Care Access, Lake Charles, California, USA. ^[11] Eastside Research Associates, Redmond, Washington, USA. ^[12] Monroe Biomedical Research, Monroe, North Carolina, USA. ^[13] Cook County Health, Chicago, Illinois, USA. ^[14] Indago Research and Health Center, Hialeah, Florida, USA. ^[15] Franciscan Health Indianapolis Hospital, Indianapolis, Indiana, USA. ^[16] Georgetown University Medical Center, Washington D.C., USA. ^[17] Stanford University School of Medicine, Palo Alto, California, USAand. ^[18] Eli Lilly and Company, Indianapolis, Indiana, USA. ^[19]

关键词 COVID-19 bamlanivimab etesevimab persistently high viral load

主题词抗体, 中和(Antibodies, Neutralizing);儿童(Child);人类(Humans);中年人(Middle Aged);预后(Prognosis);病毒载量(Viral Load)

DOI 10.1093/cid/ciab912

PMID 34718468

发布时间 2022-12-07

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准确一般字义偏差语意偏离译文作用小提交