The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis.

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第一作者： Guillaume,Holzer

第一单位： Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, Aachen, Germany.

作者： Guillaume,Holzer ^[1] ; Paola,De Magistris ^[2] ; Cathrin,Gramminger ^[3] ; Ruchika,Sachdev ^[3] ; Adriana,Magalska ^[3] ; Allana,Schooley ^[3] ; Anja,Scheufen ^[1] ; Birgitt,Lennartz ^[1] ; Marianna,Tatarek-Nossol ^[1] ; Hongqi,Lue ^[1] ; Monika I,Linder ^[4] ; Ulrike,Kutay ^[4] ; Christian,Preisinger ^[5] ; Daniel,Moreno-Andres ^[1] ; Wolfram,Antonin ^[1]

作者单位： Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, Aachen, Germany. ^[1] Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, Aachen, Germany.;Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany. ^[2] Friedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany. ^[3] Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. ^[4] Proteomics Facility, Interdisciplinary Centre for Clinical Research (IZKF), Medical School, RWTH Aachen University, Aachen, Germany. ^[5]

关键词 Nup50 RCC1 Xenopus egg extracts mitotic exit nuclear pore complex assembly