换一批mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma.
第一作者：
Zhaoming,Lu
第一单位：
State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, China.;Collaborative Innovation Center of Cancer Chemoprevention, Zhengzhou, 450001, Henan Province, China.
作者：
医学主题词
动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);疾病模型, 动物(Disease Models, Animal);药物协同作用(Drug Synergism);食管肿瘤(Esophageal Neoplasms);人类(Humans);免疫表型分型(Immunophenotyping);吲哚类(Indoles);异硫氰酸盐类(Isothiocyanates);小鼠(Mice);模型, 生物学(Models, Biological);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);嘌呤类(Purines);信号传导(Signal Transduction);亚砜类(Sulfoxides);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1007/s11033-021-06895-9
PMID
34731371
发布时间
2022-03-28
- 浏览1
Molecular biology reports
451-461页
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