Clinicopathological significance of CD28 overexpression in adult T-cell leukemia/lymphoma.

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作者： Yuma,Sakamoto ^[1] ; Takashi,Ishida ^[2] ; Ayako,Masaki ^[1] ; Morishige,Takeshita ^[3] ; Hiromi,Iwasaki ^[4] ; Kentaro,Yonekura ^[5] ; Yukie,Tashiro ^[6] ; Asahi,Ito ^[7] ; Shigeru,Kusumoto ^[7] ; Shinsuke,Iida ^[7] ; Atae,Utsunomiya ^[8] ; Ryuzo,Ueda ^[9] ; Hiroshi,Inagaki ^[1]

作者单位： Department of Pathology and Molecular Diagnostics, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. ^[1] Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan. ^[2] Department of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan. ^[3] Department of Hematology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan. ^[4] Department of Dermatology, Imamura General Hospital, Kagoshima, Japan. ^[5] Department of Pathology, Imamura General Hospital, Kagoshima, Japan. ^[6] Department of Hematology and Oncology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. ^[7] Department of Hematology, Imamura General Hospital, Kagoshima, Japan. ^[8] Department of Tumor Immunology, School of Medicine, Aichi Medical University, Nagakute, Japan. ^[9]

关键词 CD28 CD80 (B7-1)CD86 (B7-2)adult T-cell leukemia/lymphoma costimulatory molecule genetic alterations immunohistochemistry overexpression prognosis