首页> Nature communications> Pseudoknot length modulates the folding, conformational dynamics, and robustness of Xrn1 resistance of flaviviral xrRNAs.

Pseudoknot length modulates the folding, conformational dynamics, and robustness of Xrn1 resistance of flaviviral xrRNAs.

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第一作者： Xiaolin,Niu

第一单位： Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

作者： Xiaolin,Niu ^[1] ; Ruirui,Sun ^[2] ; Zhifeng,Chen ^[3] ; Yirong,Yao ^[2] ; Xiaobing,Zuo ^[4] ; Chunlai,Chen ^[5] ; Xianyang,Fang ^[6]

作者单位： Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China. ^[1] Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.;Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, 100084, China. ^[2] Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.;State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China. ^[3] X-ray Science Division, Argonne National Laboratory, Lemont, IL, 60439, USA. ^[4] Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China. chunlai@mail.tsinghua.edu.cn.;Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, 100084, China. chunlai@mail.tsinghua.edu.cn. ^[5] Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China. fangxy@mail.tsinghua.edu.cn. ^[6]

医学主题词黄病毒属(Flavivirus);核酸构象(Nucleic Acid Conformation)

DOI 10.1038/s41467-021-26616-x

PMID 34741027

发布时间 2021-12-27

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