MYC overexpression is associated with an early disease progression from MDS to AML.

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作者： David,Gajzer ^[1] ; Constantine N,Logothetis ^[2] ; David A,Sallman ^[3] ; Gregoire,Calon ^[4] ; Abida,Babu ^[2] ; Onyee,Chan ^[3] ; Nicole D,Vincelette ^[3] ; Virginia O,Volpe ^[3] ; Najla H,Al Ali ^[3] ; Pukhraz,Basra ^[1] ; Chetasi,Talati ^[3] ; Andrew T,Kuykendall ^[3] ; Qianxing,Mo ^[5] ; Eric,Padron ^[3] ; Kendra,Sweet ^[3] ; Rami S,Komrokji ^[3] ; Jeffrey E,Lancet ^[3] ; Seongseok,Yun ^[6] ; Ling,Zhang ^[7]

作者单位： Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. ^[1] University of South Florida, Internal Medicine, Tampa, FL, USA. ^[2] Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. ^[3] University of South Florida, College of Medicine, USA. ^[4] Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. ^[5] Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Seongseok.Yun@moffitt.org. ^[6] Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA. Electronic address: Ling.Zhang@moffitt.org. ^[7]

关键词 AML MDS MYC

主题词成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);疾病恶化(Disease Progression);女(雌)性(Female);随访研究(Follow-Up Studies);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);骨髓增生异常综合征(Myelodysplastic Syndromes);肿瘤, 继发原发性(Neoplasms, Second Primary);预后(Prognosis);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);回顾性研究(Retrospective Studies);存活率(Survival Rate);青年人(Young Adult)

DOI 10.1016/j.leukres.2021.106733

PMID 34749168

发布时间 2022-12-02

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Leukemia research

2021年111卷

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MYC overexpression is associated with an early disease progression from MDS to AML.

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MYC overexpression is associated with an early disease progression from MDS to AML.

Leukemia research

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Leukemia research

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