Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis.

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作者： Steven,de Maat ^[1] ; Chantal C,Clark ^[1] ; Arjan D,Barendrecht ^[1] ; Simone,Smits ^[1] ; Nadine D,van Kleef ^[1] ; Hinde,El Otmani ^[1] ; Manon,Waning ^[1] ; Marc,van Moorsel ^[1] ; Michael,Szardenings ^[2] ; Nicolas,Delaroque ^[3] ; Kristof,Vercruysse ^[3] ; Rolf T,Urbanus ^[4] ; Silvie,Sebastian ^[1] ; Peter J,Lenting ^[1] ; Christoph E,Hagemeyer ^[5] ; Thomas,Renné ^[6] ; Karen,Vanhoorelbeke ^[7] ; Claudia,Tersteeg ^[8] ; Coen,Maas ^[8]

作者单位： Central Diagnostic Laboratory Research, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. ^[1] Epitopic, Leipzig, Germany. ^[2] Ligand Development Unit, Fraunhofer IZI, Leipzig, Germany. ^[3] TargED Biopharmaceuticals, Utrecht, The Netherlands. ^[4] Laboratory for Haemostasis, Inflammation and Thrombosis, INSERM Unité Mixte de Recherche 1176, Université Paris-Saclay, Le Kremlin-Bicêtre, France. ^[5] Australian Centre for Blood Diseases, Monash University, Melbourne, Australia. ^[6] Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; and. ^[7] Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium. ^[8]