A metaproteomic-based gut microbiota profiling in children affected by autism spectrum disorders.

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第一作者： Stefano,Levi Mortera

第一单位： Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

作者： Stefano,Levi Mortera ^[1] ; Pamela,Vernocchi ^[1] ; Ilaria,Basadonne ^[2] ; Alessandro,Zandonà ^[3] ; Marco,Chierici ^[4] ; Martina,Durighello ^[1] ; Valeria,Marzano ^[1] ; Simone,Gardini ^[5] ; Antonio,Gasbarrini ^[6] ; Andrea,Urbani ^[7] ; Stefano,Vicari ^[8] ; Paola,Roncada ^[9] ; Cesare,Furlanello ^[4] ; Paola,Venuti ^[2] ; Lorenza,Putignani ^[10]

作者单位： Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. ^[1] Department of Psychology and Cognitive Sciences, University of Trento, Rovereto, Italy. ^[2] Department of Information Engineering, University of Padua, Italy. ^[3] Bruno Kessler Foundation, Trento, Italy. ^[4] GENOMEUP S.R.L., Rome, Italy. ^[5] Istituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Rome, Italy; UOC Medicina Interna e Gastroenterologia, Area Gastroenterologia ed Oncologia Medica, Dipartimento di Scienze Gastroenterologiche, Endocrino-Metaboliche e Nefro-Urologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. ^[6] Clinical Chemistry, Biochemistry and Molecular Biology Operations (UOC), Agostino Gemelli Foundation University Hospital IRCCS, Rome, Italy; Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Catholic University of Sacred Heart, Rome, Italy. ^[7] Department of Neuroscience, Unit of Head Child & Adolescent Psychiatry, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Life Sciences and Public Health, Catholic University of Sacred Heart, Rome, Italy. ^[8] Department of Health Sciences, University 'Magna Græcia' of Catanzaro, Catanzaro, Italy. ^[9] Department of Diagnostics and Laboratory Medicine, Unit of Microbiology and Diagnostic Immunology, Unit of Microbiomics and Multimodal Laboratory Medicine Research Area, Unit of Human Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address: lorenza.putignani@opbg.net. ^[10]

关键词 Autism Spectrum Disorders (ASD)Gut microbiota Mass spectrometry Metaproteomics SWATH

主题词老年人(Aged);儿童(Child);色谱法, 液相(Chromatography, Liquid);人类(Humans);RNA, 核糖体, 16S(RNA, Ribosomal, 16S);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.jprot.2021.104407

PMID 34763095

发布时间 2022-02-25

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