<i>Panax ginseng</i> and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects.
第一作者:
Yan,Wan
第一单位:
State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
作者:
关键词
5-FU, 5-fluorouracilADM, AdriamycinALT, alanine aminotransferaseAMO, Atractylodes macrocephala volatile oilAMPK, AMP-activated protein kinaseARE, antioxidant response elementAST, aspartate aminotransferaseBMNC, bone marrow nucleated cellsCIA, chemotherapy-induced hair lossCK, compound KCP, cisplatinCY, cyclophosphamideCYP2E1, Cytochrome P450 E1ChemotherapyDAC, doses of docetaxel, doxorubicin as well as cyclophosphamideERG, enzyme-treated eRGERK, extracellular signal-regulated kinasesFBG, fermented black ginsengFRG, probiotic-fermented eRGFRGE, fermented red ginseng extractGM-CSF, granulocyte macrophage colony-stimulating factorGinsenosidesHEI-OC1, House Ear Institute-Organ of Corti 1HO-1, heme oxygenase-1HSPCS, haematopoietic stem and progenitor cellsIL, interleukinJNK, c-jun N-terminal kinaseKG-KH, the mixture of ginsenosides Rk3 and Rh4LLC-PK1, porcine renal proximal epithelial tubularLSK, Lin?Sca-1+c-kit+MAPK, mitogen-activated protein kinaseMDA, malonaldehydeMEK, mitogen activated protein kinaseMKK4, mitogen activated protein kinase kinase 4MechanismNF-κB, nuclear factor-kappa B p65NQO, NAD (P) H quinone oxidoreductaseNrf2, nuclear factor erythroid related factor 2PGPG, Panax ginsengPGFR, PG flowerPGLF, PG leafPGRT, PG rootPGS, PG total saponinsPGSD, PG seedsPGSM, PG stemPI3K, phosphatidylinositol 3-kinasePPD, protopanaxadiolPPT, protopanaxatriolPharmacological effectsRG, red ginsengRGE, red ginseng extractROS, reactive oxygen speciesSREBP-1, sterol regulatory element binding protein 1Side effectsTNF-α, tumor necrosis factor-αeRG, 50 ethanol-extracted RGmTOR, mammalian target of rapamycinwRG, water-extracted RG
DOI
10.1016/j.jgr.2021.03.001
PMID
34764717
发布时间
2023-11-08
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Journal of ginseng research
617-630页
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