首页> International journal of cancer> CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells.

CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells.

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第一作者： Yi,Liu

第一单位： Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.;Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory (EMBL) and Heidelberg University Hospital, Heidelberg, Germany.

作者： Yi,Liu ^[1] ; Sanmei,Wang ^[2] ; Maria-Luisa,Schubert ^[3] ; Annika,Lauk ^[3] ; Hao,Yao ^[3] ; Maximilian Felix,Blank ^[3] ; Chunhong,Cui ^[4] ; Maike,Janssen ^[3] ; Christina,Schmidt ^[3] ; Stefanie,Göllner ^[3] ; Christian,Kleist ^[5] ; Fengbiao,Zhou ^[3] ; Jens-Ulrich,Rahfeld ^[6] ; Tim,Sauer ^[3] ; Michael,Schmitt ^[3] ; Carsten,Müller-Tidow ^[1]

作者单位： Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.;Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory (EMBL) and Heidelberg University Hospital, Heidelberg, Germany. ^[1] Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.;Department of Hematology, First Affiliated Hospital of Nanjing Medical University, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, China. ^[2] Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany. ^[3] Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany.;Shanghai University of Medicine and Health Sciences, Shanghai, China. ^[4] Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany. ^[5] Fraunhofer Institute for Cell Therapy and Immunology IZI, Halle, Germany. ^[6]

关键词 CD33 CD33-editing CRISPR/Cas9 acute myeloid leukemia chimeric antigen receptor T cells gemtuzumab ozogamicin hematopoietic stem and progenitor cells third generation CAR T cells

医学主题词造血干细胞移植(Hematopoietic Stem Cell Transplantation);造血干细胞(Hematopoietic Stem Cells);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);白血病, 髓样, 急性(Leukemia, Myeloid, Acute)

DOI 10.1002/ijc.33865

PMID 34766343

发布时间 2022-02-14

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