Microcrystalline silica particles induce inflammatory response via pyroptosis in primary human respiratory epithelial cells.

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作者： Shangya,Chen ^[1] ; Bing,Han ^[2] ; Xiao,Geng ^[3] ; Peng,Li ^[1] ; Martin F,Lavin ^[1] ; Abrey J,Yeo ^[1] ; Chao,Li ^[4] ; Jiayin,Sun ^[1] ; Cheng,Peng ^[4] ; Hua,Shao ^[1] ; Zhongjun,Du ^[1]

作者单位： Department of Toxicology, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China. ^[1] Department of Basic Research & International Cooperation, Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, Guangdong, China. ^[2] Department of Head and Neck Surgery, Affiliated Hospital of Shandong Academy of Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China. ^[3] The University of Queensland Centre for Clinical Research (UQCCR), The University of Queensland, Brisbane, Australia. ^[4] Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Brisbane, Australia. ^[5]

关键词 ceRNA human primary airway epithelial cells inflammation microcrystalline silica pyroptosis

主题词上皮细胞(Epithelial Cells);人类(Humans);炎性体(Inflammasomes);微RNAs(MicroRNAs);呼吸系统(Respiratory System);二氧化硅(Silicon Dioxide)

DOI 10.1002/tox.23405

PMID 34766707

发布时间 2022-05-31

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