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Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial.

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作者单位: IRCCS Istituto Giannina Gaslini, UOSID Centro Trial, PRINTO, Genova, Italy. Electronic address: nicolaruperto@gaslini.org. [1] College of Medicine, University of Cincinnati, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. [2] Regional Children's Hospital, Ivano-Frankivsk, Ukraine. [3] Regional Unit of Rheumatology and Osteoporosis at Central Hospital, Faculty of Medicine, San Luis Potosí, Mexico. [4] Centro Médico Privado de Reumatologia, Tucumán, Argentina. [5] Vinnytsya National Medical University N Pirogov, Vinnytsya, Ukraine. [6] Division of Rheumatology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. [7] Togliatti City Clinical Hospital number 5, Togliatti, Russia. [8] Pediatric Rheumatology Unit and Department of Pediatrics, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. [9] Adolescent Rheumatology Columbia University Medical Center, New York, NY, USA. [10] Augusta University Medical Center, Augusta, GA, USA. [11] Augusta University Medical Center, Augusta, GA, USA; Randall Children's Hospital at Legacy Emanuel, Portland, OR, USA. [12] Department of Pediatric Rheumatology, Ümraniye Training and Research Hospital, Istanbul, Turkey. [13] Pediatric Rheumatology, Atrium Health Levine Children's Hospital, Charlotte, NC, USA. [14] Departments of Pediatrics and Human Genetics, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, GA, USA. [15] Institute of Children's Health, University Children's Clinical Hospital, Sechenov University, Moscow, Russia. [16] Pediatric Rheumatology Service, Ruth Rappaport Children's Hospital, Rambam Medical Center, Haifa, Israel. [17] Saint Petersburg State Pediatric Medical University, Saint-Petersburg, Russia. [18] Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. [19] Division of Rheumatology, Seattle Children's Hospital, Seattle, WA, USA. [20] Department of Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada. [21] Division of Rheumatology, Connecticut Children's Medical Center, Hartford, and Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA. [22] Pediatric Rheumatology Unit, Department of Pediatrics, Meir Medical Centre, Kfar Saba, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. [23] CAICI Institute, Rosario City, Argentina. [24] Pfizer, New York, NY, USA. [25] Pfizer, Groton, CT, USA. [26] Pfizer, Collegeville, PA, USA. [27] Università degli Studi di Genova, Genova, Italy. [28]
DOI 10.1016/S0140-6736(21)01255-1
PMID 34767764
发布时间 2022-05-24
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