Kaempferol Has Potent Protective and Antifibrillogenic Effects for α-Synuclein Neurotoxicity In Vitro.

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作者： Masatoshi,Inden ^[1] ; Ayaka,Takagi ^[1] ; Hazuki,Kitai ^[1] ; Taisei,Ito ^[1] ; Hisaka,Kurita ^[1] ; Ryo,Honda ^[2] ; Yuji O,Kamatari ^[2] ; Sora,Nozaki ^[3] ; Xiaopeng,Wen ^[4] ; Masanori,Hijioka ^[5] ; Yoshihisa,Kitamura ^[5] ; Isao,Hozumi ^[5]

作者单位： Laboratory of Medical Therapeutics and Molecular Therapeutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan. ^[1] The United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. ^[2] Institute for Glyco-core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. ^[3] Life Science Research Center, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. ^[4] Laboratory of Pharmacology and Neurobiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu 525-8577, Japan. ^[5] Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan. ^[6]

关键词 Parkinson’s disease autophagy dementia with Lewy bodies kaempferol multiple system atrophy synucleinopathies α-synuclein