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Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?

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第一作者： Samar K,Alselehdar

第一单位： Department of Pharmacology, Physiology, and Neuroscience, Rutgers, The State University of NJ, Newark, NJ 07103, USA.

作者： Samar K,Alselehdar ^[1] ; Monami,Chakraborty ^[1] ; Suman,Chowdhury ^[1] ; Roy N,Alcalay ^[2] ; Matthew,Surface ^[2] ; Robert,Ledeen ^[1]

作者单位： Department of Pharmacology, Physiology, and Neuroscience, Rutgers, The State University of NJ, Newark, NJ 07103, USA. ^[1] Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA. ^[2]

关键词 GBA variant of Parkinson’s GD1a ganglioside GM1 ganglioside HPTLC PBMCs cholera toxin B early diagnosis sporadic Parkinson’s disease

医学主题词老年人(Aged);血液化学分析(Blood Chemical Analysis);病例对照研究(Case-Control Studies);早期诊断(Early Diagnosis);女(雌)性(Female);G(M1)神经节苷脂(G(M1) Ganglioside);神经节苷脂类(Gangliosides);葡糖苷酰鞘氨醇酶(Glucosylceramidase);人类(Humans);白细胞, 单核(Leukocytes, Mononuclear);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);帕金森病(Parkinson Disease);ROC曲线(ROC Curve)

DOI 10.3390/ijms222111522

PMID 34768952

发布时间 2024-04-07

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International journal of molecular sciences

2021年22卷21期

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Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?

International journal of molecular sciences

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International journal of molecular sciences

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Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson's Disease?

International journal of molecular sciences

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International journal of molecular sciences

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