Time-dependent dual effect of NLRP3 inflammasome in brain ischaemia.

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第一作者： Alejandra,Palomino-Antolin

第一单位： Molecular Neuroinflammation and Neuronal Plasticity Research Laboratory, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria-Hospital Universitario de la Princesa, Madrid, Spain.

作者： Alejandra,Palomino-Antolin ^[1] ; Paloma,Narros-Fernández ^[2] ; Víctor,Farré-Alins ^[1] ; Javier,Sevilla-Montero ^[2] ; Celine,Decouty-Pérez ^[1] ; Ana Belen,Lopez-Rodriguez ^[2] ; Nuria,Fernández ^[3] ; Luis,Monge ^[1] ; Ana I,Casas ^[2] ; María José,Calzada ^[1] ; Javier,Egea ^[2]

作者单位： Molecular Neuroinflammation and Neuronal Plasticity Research Laboratory, Hospital Universitario Santa Cristina, Instituto de Investigación Sanitaria-Hospital Universitario de la Princesa, Madrid, Spain. ^[1] Instituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, Facultad de Medicina, UAM, Madrid, Spain. ^[2] Instituto de Investigacion Sanitaria Princesa (IIS-IP), Department of Medicine, School of Medicine, Universidad Autonoma of Madrid, Madrid, Spain. ^[3] Fluorescence Imaging Group, Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain. ^[4] Department of Pharmacology and Personalised Medicine, MHeNs, Maastricht University, Maastricht, The Netherlands. ^[5] Department of Neurology, University Clinics Essen, Essen, Germany. ^[6]

关键词 NLRP3 inflammasome blood brain barrier immune system inflammation ischaemic stroke