Micronutritional supplementation with a holoBLG-based FSMP (food for special medical purposes)-lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect.

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作者： Sheriene Moussa,Afify ^[1] ; Andreas,Regner ^[2] ; Luis F,Pacios ^[3] ; Bart R,Blokhuis ^[1] ; Sebastian A,Jensen ^[4] ; Frank A,Redegeld ^[5] ; Isabella,Pali-Schöll ^[2] ; Karin,Hufnagl ^[5] ; Rodolfo,Bianchini ^[1] ; Sonja,Guethoff ^[2] ; Matthias F,Kramer ^[1] ; Alessandro,Fiocchi ^[1] ; Zdenek,Dvorak ^[6] ; Erika,Jensen-Jarolim ^[7] ; Franziska,Roth-Walter ^[6]

作者单位： Comparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna and University of Vienna, Vienna, Austria. ^[1] Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. ^[2] Laboratory Medicine and Immunology Department, Faculty of Medicine, Menoufia University, Shibin El Kom, Egypt. ^[3] Biotechnology Department, ETSIAAB, Center for Plant Biotechnology and Genomics, CBGP (UPM-INIA), Technical University of Madrid, Madrid, Spain. ^[4] Division of Pharmacology, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. ^[5] Bencard Allergie GmbH, Munich, Germany. ^[6] Allergy Therapeutics, Worthing, UK. ^[7] Childrens Hospital Bambino Gesù, Rome, Italy. ^[8] Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Olomouc, Czech Republic. ^[9] Biomedical International R+D GmbH, Vienna, Austria. ^[10]

关键词 beta-lactoglobulin farm effect food for special medical purposes FSMP holoBLG lozenge immune resilience immunomodulation