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Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection.

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第一作者： Daniel,Delitto

第一单位： Department of Surgery, Stanford University School of Medicine, Stanford, USA.;Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, USA.

作者： Daniel,Delitto ^[1] ; Daniel J,Zabransky ^[2] ; Fangluo,Chen ^[2] ; Elizabeth D,Thompson ^[3] ; Jacquelyn W,Zimmerman ^[2] ; Todd D,Armstrong ^[2] ; James M,Leatherman ^[2] ; Reecha,Suri ^[4] ; Tamara Y,Lopez-Vidal ^[2] ; Amanda L,Huff ^[2] ; Melissa R,Lyman ^[2] ; Samantha R,Guinn ^[2] ; Marina,Baretti ^[2] ; Luciane T,Kagohara ^[2] ; Won Jin,Ho ^[2] ; Nilofer S,Azad ^[2] ; William R,Burns ^[4] ; Jin,He ^[4] ; Christopher L,Wolfgang ^[5] ; Richard A,Burkhart ^[4] ; Lei,Zheng ^[4] ; Mark,Yarchoan ^[2] ; Neeha,Zaidi ^[2] ; Elizabeth M,Jaffee ^[3]

作者单位： Department of Surgery, Stanford University School of Medicine, Stanford, USA.;Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, USA. ^[1] The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, USA.;The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, USA.;The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, USA. ^[2] The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, USA.;The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, USA.;The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, USA.;Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, USA. ^[3] Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, USA.;The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, USA.;The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, USA.;The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, USA. ^[4] Department of Surgery, New York University Grossman School of Medicine, New York, USA. ^[5]

关键词 Pancreatic adenocarcinoma hydrogel immunotherapy neoantigen surgery vaccine