首页> Cell reports> Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.

Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.

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第一作者： Szi Kay,Leung

第一单位： University of Exeter, Exeter, UK.

作者： Szi Kay,Leung ^[1] ; Aaron R,Jeffries ^[1] ; Isabel,Castanho ^[2] ; Ben T,Jordan ^[3] ; Karen,Moore ^[1] ; Jonathan P,Davies ^[1] ; Emma L,Dempster ^[1] ; Nicholas J,Bray ^[4] ; Paul,O'Neill ^[1] ; Elizabeth,Tseng ^[5] ; Zeshan,Ahmed ^[6] ; David A,Collier ^[6] ; Erin D,Jeffery ^[3] ; Shyam,Prabhakar ^[7] ; Leonard,Schalkwyk ^[8] ; Connor,Jops ^[9] ; Michael J,Gandal ^[9] ; Gloria M,Sheynkman ^[10] ; Eilis,Hannon ^[1] ; Jonathan,Mill ^[11]

作者单位： University of Exeter, Exeter, UK. ^[1] University of Exeter, Exeter, UK; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. ^[2] Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA. ^[3] School of Medicine, Cardiff University, Cardiff, UK. ^[4] Pacific Biosciences, Menlo Park, CA, USA. ^[5] Eli Lilly & Co., Windlesham, UK. ^[6] Genome Institute of Singapore, Agency for Science, Technology and Research (A(∗)STAR), Singapore, Singapore. ^[7] School of Life Sciences, University of Essex, Colchester, UK. ^[8] Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA. ^[9] Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; UVA Cancer Center, University of Virginia, Charlottesville, VA, USA. ^[10] University of Exeter, Exeter, UK. Electronic address: J.mill@exeter.ac.uk. ^[11]

关键词 isoform, transcript, expression, brain, cortex, mouse, human, adult, fetal, long-read sequencing, alternative splicing