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Genetic and genomic analysis of acute lymphoblastic leukemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials.

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第一作者： Thomas,Creasey

第一单位： Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne. tom.creasey@ncl.ac.uk.

作者： Thomas,Creasey ^[1] ; Emilio,Barretta ^[2] ; Sarra L,Ryan ^[2] ; Ellie,Butler ^[2] ; Amy A,Kirkwood ^[3] ; Daniel,Leongamornlert ^[4] ; Elli,Papaemmanuil ^[5] ; Pip,Patrick ^[3] ; Laura,Clifton-Hadley ^[3] ; Bela,Patel ^[6] ; Tobias,Menne ^[7] ; Andrew K,McMillan ^[8] ; Christine J,Harrison ^[2] ; Clare J,Rowntree ^[9] ; Nick,Morley ^[10] ; David I,Marks ^[11] ; Adele K,Fielding ^[12] ; Anthony V,Moorman ^[13]

作者单位： Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne. tom.creasey@ncl.ac.uk. ^[1] Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne. ^[2] Cancer Research UK and UCL Cancer Trials Centre, UCL Cancer Institute University College London. ^[3] Sanger Institute, Cambridge. ^[4] Memorial Sloan Kettering Cancer Center, New York. ^[5] Department of Haematology, Queen Mary University of London, London. ^[6] Department of Haematology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne. ^[7] Department of Haematology, Nottingham University Hospital NHS Trust, Nottingham. ^[8] Department of Haematology, Cardiff And Vale University Health Board, Cardiff. ^[9] Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield. ^[10] Department of Haematology, University Hospitals Bristol NHS Foundation Trust, Bristol. ^[11] UCL Cancer Institute, London. ^[12] Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne. anthony.moorman@ncl.ac.uk. ^[13]