CoRe: a robustly benchmarked R package for identifying core-fitness genes in genome-wide pooled CRISPR-Cas9 screens.

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作者： Alessandro,Vinceti ^[1] ; Emre,Karakoc ^[2] ; Clare,Pacini ^[2] ; Umberto,Perron ^[1] ; Riccardo Roberto,De Lucia ^[1] ; Mathew J,Garnett ^[2] ; Francesco,Iorio ^[3]

作者单位： Human Technopole, Milan, Italy. ^[1] Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. ^[2] Human Technopole, Milan, Italy. Francesco.iorio@fht.org. ^[3] Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. Francesco.iorio@fht.org. ^[4]

关键词 CRISPR-Cas9 screens algorithms benchmark cancer dependency core-fitness genes

主题词规范(Benchmarking);基因, 必要(Genes, Essential);人类(Humans);肿瘤(Neoplasms)

DOI 10.1186/s12864-021-08129-5

PMID 34789150

发布时间 2024-04-04

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