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首页> British journal of pharmacology> L6H21 protects against cognitive impairment and brain pathologies via toll-like receptor 4-myeloid differentiation factor 2 signalling in prediabetic rats.

L6H21 protects against cognitive impairment and brain pathologies via toll-like receptor 4-myeloid differentiation factor 2 signalling in prediabetic rats.

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作者： Thura Tun,Oo ^[1] ; Natticha,Sumneang ^[2] ; Benjamin,Ongnok ^[3] ; Busarin,Arunsak ^[1] ; Titikorn,Chunchai ^[2] ; Sasiwan,Kerdphoo ^[3] ; Nattayaporn,Apaijai ^[1] ; Wasana,Pratchayasakul ^[2] ; Guang,Liang ^[3] ; Nipon,Chattipakorn ^[1] ; Siriporn C,Chattipakorn ^[3]

作者单位： Neurophysiology Unit, Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. ^[1] Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. ^[2] Center of Excellence in Cardiac Electrophysiology, Chiang Mai University, Chiang Mai, Thailand. ^[3] Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China. ^[4] Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. ^[5]

关键词 cognition myeloid differentiation factor 2 neuroinflammation obesity toll-like receptor 4

主题词动物(Animals);脑(Brain);胰岛素抗药性(Insulin Resistance);男(雄)性(Male);二甲双胍(Metformin);糖尿病前期(Prediabetic State);大鼠(Rats);大鼠, Wistar(Rats, Wistar);Toll样受体4(Toll-Like Receptor 4)

DOI 10.1111/bph.15741

PMID 34796473

发布时间 2022-04-13

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British journal of pharmacology

British journal of pharmacology

2022年179卷6期

1220-1236页

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