DNAzyme-Based nanoflowers for reversing P-glycoprotein-mediated multidrug resistance in breast cancer.

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第一作者： Linna,Liang

第一单位： College of Chemistry & Environmental Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, PR China.

作者： Linna,Liang ^[1] ; Wendi,Huo ^[2] ; Bei,Wang ^[2] ; Lingzhi,Cao ^[1] ; Haoran,Huo ^[1] ; Yixin,Liu ^[2] ; Yi,Jin ^[3] ; Xinjian,Yang ^[4]

作者单位： College of Chemistry & Environmental Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, PR China. ^[1] College of Basic Medical Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases of Hebei Province, Hebei University, Baoding 071002, PR China. ^[2] College of Basic Medical Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-autoimmune Diseases of Hebei Province, Hebei University, Baoding 071002, PR China. Electronic address: jinyi2009@163.com. ^[3] College of Chemistry & Environmental Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, PR China. Electronic address: xjyang321@hbu.edu.cn. ^[4]

关键词 DNAzyme Gene silencing Multidrug resistance P-glycoprotein

主题词乳腺肿瘤(Breast Neoplasms);DNA, 催化性(DNA, Catalytic);多柔比星(Doxorubicin);抗药性, 多药(Drug Resistance, Multiple);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);人类(Humans)

DOI 10.1016/j.jcis.2021.11.031

PMID 34802770

发布时间 2021-12-16

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准确一般字义偏差语意偏离译文作用小提交