Targeted Inhibition of LPL/FABP4/CPT1 fatty acid metabolic axis can effectively prevent the progression of nonalcoholic steatohepatitis to liver cancer.
作者:
主题词
动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);肉碱O-软脂酰转移酶(Carnitine O-Palmitoyltransferase);细胞系, 肿瘤(Cell Line, Tumor);计算生物学(Computational Biology);数据库, 遗传学(Databases, Genetic);脂肪酸结合蛋白质类(Fatty Acid-Binding Proteins);基因表达调控(Gene Expression Regulation);人类(Humans);脂蛋白脂酶(Lipoprotein Lipase);肝肿瘤(Liver Neoplasms);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肿瘤干细胞(Neoplastic Stem Cells);增量调节(Up-Regulation)
DOI
10.7150/ijbs.64714
PMID
34803493
发布时间
2021-12-23
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