Stapled Peptides Targeting SARS-CoV-2 Spike Protein HR1 Inhibit the Fusion of Virus to Its Cell Receptor.

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第一作者： Mengjun,Zheng

第一单位： School of Pharmacy, Second Military Medical University, Shanghai 200433, China.

作者： Mengjun,Zheng ^[1] ; Wei,Cong ^[2] ; Haoran,Peng ^[3] ; Jie,Qing ^[4] ; Huaxing,Shen ^[2] ; Yaxin,Tang ^[1] ; Chenchen,Geng ^[1] ; Si,Chen ^[5] ; Yan,Zou ^[1] ; Wei-Dong,Zhang ^[1] ; Hong-Gang,Hu ^[2] ; Xiang,Li ^[1]

作者单位： School of Pharmacy, Second Military Medical University, Shanghai 200433, China. ^[1] Shanghai Engineering Research Center of Organ Repair, Institute of Translational Medicine, Shanghai University, Shanghai 200444, China. ^[2] Department of Microbiology, Second Military Medical University, Shanghai 200433, China. ^[3] Research Center of Integrated Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest Medical University, Luzhou 646000, China. ^[4] School of Medicine, Shanghai University, Shanghai 200444, China. ^[5]

主题词人类(Humans);肽类(Peptides);抗病毒药(Antiviral Agents);病毒内化(Virus Internalization);模型, 分子(Models, Molecular);构效关系(Structure-Activity Relationship)

DOI 10.1021/acs.jmedchem.1c01681

PMID 34818014

发布时间 2024-07-25

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