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Highly Neutralizing COVID-19 Convalescent Plasmas Potently Block SARS-CoV-2 Replication and Pneumonia in Syrian Hamsters.

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第一作者： Yuki,Takamatsu

第一单位： Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.

作者： Yuki,Takamatsu ^[1] ; Masaki,Imai ^[2] ; Kenji,Maeda ^[1] ; Noriko,Nakajima ^[3] ; Nobuyo,Higashi-Kuwata ^[1] ; Kiyoko,Iwatsuki-Horimoto ^[2] ; Mutsumi,Ito ^[2] ; Maki,Kiso ^[2] ; Tadashi,Maemura ^[2] ; Yuichiro,Takeda ^[4] ; Kazumi,Omata ^[5] ; Tadaki,Suzuki ^[3] ; Yoshihiro,Kawaoka ^[6] ; Hiroaki,Mitsuya ^[7]

作者单位： Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, Tokyo, Japan. ^[1] Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan. ^[2] Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan. ^[3] Department of Respiratory Medicine, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan. ^[4] Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.;Departments of Hematology, Rheumatology, and Infectious Diseases, Kumamoto University Hospital, Kumamoto, Japan. ^[5] Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan.;Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.;Department of Special Pathogens, International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyogrid.26999.3d, Tokyo, Japan. ^[6] Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, Tokyo, Japan.;Experimental Retrovirology Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.;Department of Clinical Sciences, Kumamoto University School of Medicine, Kumamoto, Japan. ^[7]

关键词 COVID-19 SARS-CoV-2 Syrian hamster COVID-19 model convalescent plasma therapy