Systematic analysis of potential targets of the curcumin analog pentagamavunon-1 (PGV-1) in overcoming resistance of glioblastoma cells to bevacizumab.
作者:
关键词
ADAM10, a disintegrant and metalloproteinase 10AKRs, Aldo keto reductasesBevacizumab resistanceBioinformaticsCAFs, Cancer-associated fibroblastsCOX-2, cyclooxigenase-2DEGs, differentially expressed genesDT, Direct targets of PGV-1GSTM1, glutathione S-transferase mu 1GSTP1, glutathione S-transferase Pi-1GlioblastomaHSD17B10, Human type 10 17beta-hydroxysteroid dehydrogenaseImmunotherapyKEGG, Kyoto Encyclopedia of Genes and GenomesPBR, potential therapeutic target genes of PGV-1 against bevacizumab resistance glioblastomaPGV-1PGV-1, Pentagamavunon-1PTGS2, prostaglandin-endoperoxide synthase 2ROS, reactive oxygen speciesSEA, Similarity ensemble approachTarget predictionVEGF, vascular endothelial growth factorWebgestalt, WEB-based GEne SeT AnaLysis Toolkit
DOI
10.1016/j.jsps.2021.09.015
PMID
34819791
发布时间
2022-04-28
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Saudi pharmaceutical journal
2021年29卷11期
1289-1302页
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