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MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging.

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第一作者: Denis,Schapiro
第一单位: Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Institute for Computational Biomedicine and Institute of Pathology, Faculty of Medicine, Heidelberg University Hospital and Heidelberg University, Heidelberg, Germany.
作者单位: Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Institute for Computational Biomedicine and Institute of Pathology, Faculty of Medicine, Heidelberg University Hospital and Heidelberg University, Heidelberg, Germany. [1] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. [2] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Image and Data Analysis Core, Harvard Medical School, Boston, MA, USA. [3] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA. [4] Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. [5] Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA. [6] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. [7] Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Department of Biology, Brigham Young University, Provo, UT, USA. [8] Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. [9] Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA.;Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA. [10] Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA.;Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. [11] Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA. [12] Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.;Genentech, South San Francisco, CA, USA. [13] Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. [14] Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.;Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, OR, USA. [15] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.;Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. [16] Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA. peter_sorger@hms.harvard.edu.;Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA. peter_sorger@hms.harvard.edu.;Department of Systems Biology, Harvard Medical School, Boston, MA, USA. peter_sorger@hms.harvard.edu. [17]
DOI 10.1038/s41592-021-01308-y
PMID 34824477
发布时间 2025-01-04
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