"Q-markers targeted screening" strategy for comprehensive qualitative and quantitative analysis in fingerprints of <i>Angelica dahurica</i> with chemometric methods.

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作者： Fang-Yuan,Gao ^[1] ; Hai-Yan,Chen ^[2] ; Yu-Sha,Luo ^[3] ; Ji-Kuai,Chen ^[4] ; Lang,Yan ^[1] ; Jiang-Bo,Zhu ^[1] ; Guo-Rong,Fan ^[1] ; Ting-Ting,Zhou ^[5]

作者单位： Department of Health Toxicology, Faculty of Naval Medicine, Second Military Medical University, No. 800 Xiangyin Road, Shanghai 200433, China. ^[1] Department of Endocrinology, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Shanghai 200003, China. ^[2] Department of Pharmaceutical Analysis, School of Pharmacy, Second Military Medical University, No. 325 Guohe Road, Shanghai 200433, China. ^[3] Shanghai Key Laboratory for Pharmaceutical Metabolite Research, School of Pharmacy, Second Military Medical University, No. 325 Guohe Road, Shanghai 200433, China. ^[4] Department of Clinical Pharmacy, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200025, China. ^[5] School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China. ^[6]

关键词 ANOVA, analysis of variance ASE, accelerated solvent extraction Accelerated solvent extraction Angelica dahurica BBD, Box-Bohnken Design CID, collision-induced-dissociation Chemometric analysis HCA, hierarchical cluster analysis HPLC-PDA-ESI-ITMSn, high performance liquid chromatography-photo diode array-electrospray ionization ion trap mass spectrometry HRE, heated reflux extraction IS, internal standard LDA, linear discriminant analysis LOD, limits of detection LOQ, limits of quantification Liquid chromatography tandem mass spectrometry MAE, microwave-assisted extraction Q-markers targeted screening Qualitative markers Quantitative markers RSD, relative standard deviation RSM, response surface methodology S/N, signal-to-noise ratios SA, similarity analysis TOF, time of fight UAME, ultrasonic-assisted microwave extraction UE, ultrasonic extraction UV, ultra violet bergapten (PubChem CID: 2355)estazolam (PubChem CID: 3261)hydrate oxypeucedanin (PubChem CID: 17536)imperatorin (PubChem CID: 10212)isoimperatorin (PubChem CID: 68081)oxypeucedanin (PubChem CID: 160544)phellopterin (PubChem CID: 98608)prangenin hydrate (PubChem CID: 129710912)xanthotoxin (PubChem CID: 4114)xanthotoxol (PubChem CID: 65090)

DOI 10.1016/j.fochx.2021.100162

PMID 34825171

发布时间 2021-11-27

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Food chemistry

2021年12卷

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"Q-markers targeted screening" strategy for comprehensive qualitative and quantitative analysis in fingerprints of <i>Angelica dahurica</i> with chemometric methods.

Food chemistry

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Food chemistry

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"Q-markers targeted screening" strategy for comprehensive qualitative and quantitative analysis in fingerprints of <i>Angelica dahurica</i> with chemometric methods.

Food chemistry

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Food chemistry

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