Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers.

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作者： Keishi,Kisoh ^[1] ; Go,Sugahara ^[1] ; Yuko,Ogawa ^[1] ; Suzue,Furukawa ^[1] ; Yuji,Ishida ^[1] ; Takeshi,Okanoue ^[2] ; Michinori,Kohara ^[3] ; Chise,Tateno ^[4]

作者单位： Research and Development Department, PhoenixBio Co., Ltd., 3-4-1 Kagamiyama, Higashihiroshima 739-0046, Japan. ^[1] Research Center for Hepatology and Gastroenterology, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. ^[2] Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, 1-2 Kawazonocho, Suita 564-0013, Japan. ^[3] Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan. ^[4]

关键词 Mallory–Denk body NAFLD/NASH ballooning hepatocytes human disease animal model human liver chimeric mice

DOI 10.3390/biomedicines9111647

PMID 34829876

发布时间 2024-04-04

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Biomedicines

2021年9卷11期

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Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers.

Biomedicines

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Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers.

Biomedicines

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Biomedicines

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