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Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome.

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第一作者： Gokul,Swaminathan

第一单位： Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA.

作者： Gokul,Swaminathan ^[1] ; Michael,Citron ^[2] ; Jianying,Xiao ^[2] ; James E,Norton ^[1] ; Abigail L,Reens ^[1] ; Begüm D,Topçuoğlu ^[1] ; Julia M,Maritz ^[1] ; Keun-Joong,Lee ^[3] ; Daniel C,Freed ^[2] ; Teresa M,Weber ^[2] ; Cory H,White ^[1] ; Mahika,Kadam ^[1] ; Erin,Spofford ^[4] ; Erin,Bryant-Hall ^[4] ; Gino,Salituro ^[3] ; Sushma,Kommineni ^[1] ; Xue,Liang ^[1] ; Olga,Danilchanka ^[1] ; Jane A,Fontenot ^[5] ; Christopher H,Woelk ^[1] ; Dario A,Gutierrez ^[1] ; Daria J,Hazuda ^[6] ; Geoffrey D,Hannigan ^[1]

作者单位： Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA. ^[1] Infectious Diseases and Vaccine Research, MRL, Merck & Co., Inc., West Point, PA 19486, USA. ^[2] Pharmacokinetics, Pharmacodynamics & Drug Metabolism, MRL, Merck & Co. Inc., Rahway, NJ 07065, USA. ^[3] Safety Assessment and Laboratory Animal Research, MRL, Merck & Co. Inc., Boston, MA 02115, USA. ^[4] New Iberia Research Center, University of Louisiana at Lafayette, Lafayette, LA 70503, USA. ^[5] Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA.;Infectious Diseases and Vaccine Research, MRL, Merck & Co., Inc., West Point, PA 19486, USA. ^[6]

关键词 immunity microbiome vaccines

DOI 10.3390/vaccines9111340

PMID 34835271

发布时间 2021-11-30

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Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome.

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Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome.

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