Synthesis, anticancer evaluation and molecular docking of new benzothiazole scaffolds targeting FGFR-1.
第一作者:
Eman A,Abd El-Meguid
第一单位:
Department of Chemistry of Natural and Microbial Products, National Research Centre, Dokki, Cairo 12622, Egypt. Electronic address: emannrc@yahoo.com.
作者:
医学主题词
抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);苯并噻唑类(Benzothiazoles);细胞周期(Cell Cycle);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);分子结构(Molecular Structure);蛋白激酶抑制剂(Protein Kinase Inhibitors);受体, 成纤维细胞生长因子, 1型(Receptor, Fibroblast Growth Factor, Type 1);构效关系(Structure-Activity Relationship)
DOI
10.1016/j.bioorg.2021.105504
PMID
34836644
发布时间
2022-02-18
- 浏览3
Bioorganic chemistry
105504页
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