Single-cell atlas of splenocytes reveals a critical role of a novel plasma cell‒specific marker Hspa13 in antibody class-switching recombination and somatic hypermutation.

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第一作者： Bing,Zhai

第一单位： Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China; Department of Geriatric Hematology, Chinese PLA General Hospital, Beijing 100853, China.

作者： Bing,Zhai ^[1] ; Xiaoling,Liu ^[2] ; Yaqi,Xu ^[3] ; Gaizhi,Zhu ^[3] ; Shan,Zhou ^[3] ; Youdi,He ^[4] ; Xiaoqian,Wang ^[5] ; Wenting,Su ^[6] ; Gencheng,Han ^[7] ; Renxi,Wang ^[8]

作者单位： Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China; Department of Geriatric Hematology, Chinese PLA General Hospital, Beijing 100853, China. ^[1] Department of Dermatology, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, China. ^[2] Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China. ^[3] Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. ^[4] Staidson (Beijing) Biopharmaceuticals Co., Ltd, Beijing 100176, China. ^[5] Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China. Electronic address: wtsu@ccmu.edu.cn. ^[6] Beijing Institute of Basic Medical Sciences, Beijing 100850, China. Electronic address: genchenghan@163.com. ^[7] Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing 100069, China. Electronic address: renxi_wang@ccmu.edu.cn. ^[8]

关键词 B cells Hspa13 Single-cell atlas Stch T cells