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Harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design.

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第一作者： Jeremy A,Duke

第一单位： Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA.

作者： Jeremy A,Duke ^[1] ; Amy V,Paschall ^[1] ; John,Glushka ^[2] ; Andrew,Lees ^[3] ; Kelley W,Moremen ^[4] ; Fikri Y,Avci ^[5]

作者单位： Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA. ^[1] Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA. ^[2] Fina Biosolutions, LLC, Rockville, Maryland, USA. ^[3] Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA. ^[4] Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; Center for Molecular Medicine, University of Georgia, Athens, Georgia, USA. Electronic address: avci@uga.edu. ^[5]

关键词 Streptococcus pneumoniae capsular polysaccharide galactose oxidase glycoconjugate vaccine pneumonia vaccine development