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ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.

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作者单位: Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ 85054, USA.;Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.;Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA.;Mayo Clinic Cancer Center, Phoenix, AZ 85054, USA.;Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85281, USA.;Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. [1] Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85281, USA.;School of Molecular Sciences, Arizona State University, Tempe, AZ 85251, USA. [2] School of Molecular Sciences, Arizona State University, Tempe, AZ 85251, USA.;MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI 48824.;Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824. [3] Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. [4] Computational Structural Biology and Molecular Biophysics, Beckman institute, University of Illinois, IL 61801, USA. [5] Institute of Infection Immunity and Inflammation, MRC-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. [6] Medicines Discovery Institute, School of Biosciences, Cardiff University, Cardiff CF10 3AT, UK. [7] MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI 48824.;Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824. [8] Eyring Materials Center, Arizona State University, Tempe, AZ 85281, USA. [9] Analytical Sciences, Biopharmaceutical Development, AstraZeneca, Gaithersburg, MD 20878, USA. [10] School of Pharmacy and Pharmaceutical Science, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF10 3NB, UK. [11] Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ 85054, USA.;Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.;Mayo Clinic Cancer Center, Phoenix, AZ 85054, USA. [12] Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W. Baltimore Street, MD 21201, USA.;Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore Street, MD 21201, USA. [13] Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK. [14] Microbial Sciences, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, USA. [15] Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ 85054, USA.;Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.;Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA.;Mayo Clinic Cancer Center, Phoenix, AZ 85054, USA. [16]
DOI 10.1126/sciadv.abl8213
PMID 34851659
发布时间 2024-09-23
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Science advances

2021年7卷49期

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