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Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".

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第一作者: Jonas,Bovijn
第一单位: Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.;Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
作者单位: Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.;Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. [1] Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia. [2] Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.;Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.;Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. [3] Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.;Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK. [4] Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK. [5] Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.;Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.;Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands. [6] Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK. [7] Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing 100191, China. [8] Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.;Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK. [9] Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.;Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. [10] Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.;Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.;Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.;National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK. [11] Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.;Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.;Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.;National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK. [12]
DOI 10.1126/scitranslmed.abf4530
PMID 34851696
发布时间 2025-05-30
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Science translational medicine

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