Perfect adaptation of CD8<sup>+</sup> T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation.

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第一作者： Nicola,Trendel

第一单位： Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK.

作者： Nicola,Trendel ^[1] ; Philipp,Kruger ^[1] ; Stephanie,Gaglione ^[1] ; John,Nguyen ^[1] ; Johannes,Pettmann ^[1] ; Eduardo D,Sontag ^[2] ; Omer,Dushek ^[3]

作者单位： Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK. ^[1] Radcliffe Department of Medicine, Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, OX1 3RE Oxford, UK. ^[2] Electrical and Computer Engineering and Bioengineering, Northeastern University, Boston, MA 02115, USA. ^[3]

主题词 CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);淋巴细胞活化(Lymphocyte Activation)

DOI 10.1126/scisignal.aay9363

PMID 34855472

发布时间 2024-03-04

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