Oxcarbazepine was associated with risks of newly developed hypothyroxinaemia and impaired central set point of thyroid homeostasis in schizophrenia patients.

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作者： Desheng,Zhai ^[1] ; Jinni,Chen ^[2] ; Baoqiang,Guo ^[2] ; Ravi,Retnakaran ^[2] ; Songyin,Gao ^[3] ; Xiangyang,Zhang ^[4] ; Wei,Hao ^[5] ; Ruiling,Zhang ^[1] ; Ying,Zhao ^[1] ; Shi Wu,Wen ^[1]

作者单位： Xinxiang Medical University, The Second Affiliated Hospital, Xinxiang, China. ^[1] School of Public Health, Xinxiang Medical University, Xinxiang, China. ^[2] Division of Endocrinology and Metabolism, University of Toronto, Toronto, Canada. ^[3] Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada. ^[4] Zhumadian Mental Health Center, Zhumadian, China. ^[5] School of Pharmacy, Xinxiang Medical University, Xinxiang, China. ^[6] Xinxiang Key Laboratory of Clinical psychopharmacology, Xinxiang Medical University, Xinxiang, China. ^[7] Henan International Joint Laboratory of Non-Invasive Neuro-modulation, Xinxiang Medical University, Xinxiang, China. ^[8] OMNI Research Group, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada. ^[9] School of Epidemiology and Public Health, University of Ottawa Faculty of Medicine, Ottawa, Canada. ^[10] Department of Obstetrics, Gynecology, and Newborn Care, University of Ottawa Faculty of Medicine, Ottawa, Canada. ^[11]

关键词 central set point hypothyroxinaemia oxcarbazepine schizophrenia thyroid feedback quantile-based index thyroid homeostasis thyroid stimulating hormone index

主题词内环境稳定(Homeostasis);人类(Humans);回顾性研究(Retrospective Studies);精神分裂症(Schizophrenia);甲状腺(Thyroid Gland);促甲状腺素(Thyrotropin);甲状腺素(Thyroxine)

DOI 10.1111/bcp.15163

PMID 34855997

发布时间 2022-06-26

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