Methylation and Expression of Mutant <i>FUS</i> in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients.

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作者： T,Hartung ^[1] ; M,Rhein ^[2] ; N,Kalmbach ^[3] ; N,Thau-Habermann ^[1] ; M,Naujock ^[1] ; L,Müschen ^[1] ; H,Frieling ^[4] ; J,Sterneckert ^[1] ; A,Hermann ^[3] ; F,Wegner ^[5] ; S,Petri ^[6]

作者单位： Department of Neurology, Hannover Medical School, Hannover, Germany. ^[1] Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany. ^[2] Department of Psychiatry, Social Psychiatry and Psychotherapy, Hanover Medical School, Hanover, Germany. ^[3] Evotec International GmbH, Göttingen, Germany. ^[4] Center for Regenerative Therapies TU Dresden (CRTD), Technische Universität Dresden, Dresden, Germany. ^[5] Translational Neurodegeneration Section "Albrecht Kossel", Department of Neurology and Center for Transdisciplinary Neuroscience (CTNR), University Medical Center Rostock, University of Rostock, Rostock, Germany. ^[6] German Center for Neurodegenerative Diseases (DZNE) Rostock/Greifswald, Rostock, Germany. ^[7]

关键词 DNA methyltransferases FUS amyotrophic lateral sclerosis induced pluripotent stem cells derived motor neurons methylation

DOI 10.3389/fcell.2021.774751

PMID 34869374

发布时间 2021-12-07

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Frontiers in cell and developmental biology

2021年9卷

774751页

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Methylation and Expression of Mutant <i>FUS</i> in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients.

Frontiers in cell and developmental biology

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Frontiers in cell and developmental biology

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Methylation and Expression of Mutant <i>FUS</i> in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients.

Frontiers in cell and developmental biology

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Frontiers in cell and developmental biology

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